
产品货号:
Z26776
中文名称:
SMARCD3抗体
英文名称:
Anti-SMARCD3 Antibody (N-term)
产品规格:
80μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-SMARCD3 Antibody (N-term) |
指标别名 | BAF60C;BRG1 associated factor 60C;CRACD3;Rsc6p;SMARCD3 |
克隆性 | Polyclonal |
检验物种 | human |
应用范围 | IF,WB |
基因名称 | SMARCD3 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | This SMARCD3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 27-60 amino acids from the N-terminal region of human SMARCD3. |
计算分子量 | 55kDa |
成分 | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
纯化方式 | This antibody is purified through a protein A column,followed by peptide affinity purification |
保存条件 | Maintain refrigerated at 2~8℃ for up to 2 weeks.For long term storage,store at -20℃ in small aliquots to prevent freeze-thaw cycles. |
背景资料 | Plays a role in ATP dependent nucleosome remodeling by SMARCA4 containing complexes.Stimulates nuclear receptor mediated transcription.Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron- specific chromatin remodeling complex (nBAF complex).During neural development a switch from a stem/progenitor to a post- mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state.The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes.As neural progenitors exit mitosis and differentiate into neurons,npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A,are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF).The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells.The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth (By similarity). |
Uniprot ID | Q6STE5 |
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